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What's the difference between Mace and Pepper Spray? All of Mace's products now are either straight OC Pepper Spray and /or OC /Tear gas combinations or foam. Don't get Mace confused with Pepper Spray. MACE (the actual chemical compound) has not been used for 15 years. Mace is an irritant that is very similar to tear gas. Unlike pepper spray Mace will NOT cause inflammation of the capillaries causing temporary blindness, nausea, cut off all but life support breathing and create a very strong burning or stinging sensation. It is important to note that Mace is also a brand name.