Exactly how do I spray my pepper spray? If you have to use your pepper spray make sure you have distance between you and the threat if at all possible. Aim the spray at the eyes and facial region of the threat then release a 1 to 2 second burst of spray. After you have done this MOVE out of the way but keep your eyes on the threat. Pepper spray ingredients can take a couple of moments to cause a reaction and by watching the reactions of the threat you will be able to determine if you will require another shot of pepper spray.